The dominant clinical manifestations include purpura, arthritis, abdominal. Pdf henochschonlein purpura hsp is the most common vasculitis of childhood. Henochschonlein purpura hsp is a small vessel vasculitis mediated by igaimmune complex deposition. Henochschonlein purpura hsp, the commonest childhood vasculitis, is characterised by nonthrombocytopaenic palpable purpura, arthritis or arthralgias, gastrointestinal and renal involvement. Research open access mefv gene mutations in egyptian. Henochschonlein purpura, yupingfeng san, oxidative stress, immune system, efficacy introduction henochschonlein purpura hsp is a common clinical allergic vasculitis caused by the. This is basically a selflimited disease, however the. Henochschonlein purpura hsp, also called immunoglobulin a vasculitis igav, is a vascular disease that primarily affects small blood vessels.
Henochschonlein purpura is a disease that causes small blood vessels in the body to become inffamed and leak. Serious gastrointestinal form of henochschonlein purpura induced by helicobacter pylori infection complicated with bradycardia and euthyroid sick syndrome g vijatovdjuric 1, 2, n barisic, a djuretic. In patients with hsp, the persons own immune system attacks blood vessels in the skin, intestines, joints and. This disease involves vasculitis of the small blood vessels swelling of. Hsp is an acute vasculitis that primarily affects children. Henochschonlein purpura hsp is an autoimmune, multisystem, acute vasculitis of childhood commonly involving the skin, gut, joints and the kidneys. Henoch schonlein purpura hsp affects the blood vessels and causes a spotty rash. Henoch schonlein purpura hsp is a type of vasculitis, which means inflammation of the blood vessels. Henoch schonlein purpura hsp is a systemic vasculitic disease which is common in children. The disease is characterized by abnormal deposits of immunoglobulin a an antibody in the blood vessels, leading to their inflammation vasculitis. Supportive care until recovery when there is little or no kidney involvement may. Heshe has been diagnosed with henoch schonlein purpura and is currently. The main symptom of hsp is a rash of raised red or purple spots. Henochschonlein purpura hsp is a selflimit ed vasculitis occurring mostly in children 1.
Central nervous system cns involvement in henochschonlein purpura hsp is rare but poses diagnostic difficulties. Risk factors, renal damage, henochschonlein purpura introduction henochschonlein purpura hsp is a selflimited vasculitis occurring mostly in children 1. Henochschonlein purpura henochschonlein purpura is an inflammation of the small blood vessels of the skin, joints, bowels and kidneys. Hsp is a multisystem disease affecting skin, joints. Henochschonlein purpura hsp is the most common vasculitis of childhood.
Henoch scholein purpura hsp introduction hsp is the commonest vasculitis of childhood and is selflimiting in the majority of cases. When blood vessels get inflamed, they can bleed into the skin, causing a reddishpurple rash purpura. Longterm outcome and treatment academic dissertation to be presented with the assent of the faculty of medicine, university of oulu, for public. Pdf most of the documents on the racgp website are in portable document format pdf. Pdf on aug 24, 2010, chetan mukhtyar and others published henoch schonlein purpura find, read and cite all the research you need on. By the traditional format of choosing different combinations. The american college of rheumatology 1990 criteria for the. The vast majority of people with henochschonlein purpura hsp recover on their own within several weeks. Although hsp is typically a disease of children, adult cases have been described. It is characterized by the clinical tetrad of nonthrombocytopenic palpable. Henochschonlein purpura symptoms and causes mayo clinic. Palpable purpura age files are in this category, out of 12 total.
Systemic vasculitis is a heterogeneous group of diseases characterized by inflammation and necrosis of the blood vessel walls. Vasculitis means inflammation of tiny blood vessels. Henochschonlein purpura also known as iga vasculitis, is often called hsp for short. These files will have pdf in brackets along with the filesize of the download. Pdf iga vasculitis henochschonlein purpura in children. Original article efficacy of yupingfeng san for assisting.
The exact cause of hsp is unknown and there is no specific test to diagnose. Original article risk factors for renal damage in henoch. The aetiology is unknown but the history often identifies a preceeding throaturti infection and some bacteria and viruses have been implicated. Henoch schonlein purpura gp follow up letter patient details date of ed attendance. Central nervous system involvement in henochschonlein.
Depending on the size of the involved vessels small, medium, or largevessel. Its not usually serious, but can sometimes lead to kidney problems. Hsp is an abnormal response of the bodys immune system, similar to an allergic reaction. Dudley j, smith g, llewelynedwards a, bayliss k, pike k, tizard j et al. Henochschonlein purpura or hsp is a common childhood vasculitis, most commonly occurring in children ages 3 to 15 years of age. Original article risk factors for renal damage in henochschonlein. Batasan henoch schonlein purpura adalah sindroma klinis yang disebabkan oleh vaskulitis pembuluh darah kecil sistemik, yang ditandai dengan lesi kulit spesifik yang berupa purpura non trombositopenik, artritis, atau atralgia, nyeri abdomen atau perdarahan gastrointestinal dan kadangkadang dengan nefritis. The clinical implications of adultonset henochschonelin. This smallvessel vasculitis is mediated by immunoglobulin a igacontaining immune complexes and is characterized. The body areas most commonly affected are the small blood. Henochschonlein purpura hsp, also known as iga vasculitis, is a disease of the skin. Iga vasculitishenoch schonlein purpura igavhsp is the most common childhood vasculitis in most parts of the world. What links here related changes upload file special pages permanent link page. Pdf on aug 24, 2010, chetan mukhtyar and others published henochschonlein purpura find, read and cite all the research you need on.